Micro Nano Bio Fluidics Unit

Micro Nano Bio Fluidics Unit

Our group has made exceptional contributions to the Physics of Micro/nanoscale flows, Biofluids, and Soft Matter through original research. We have addressed complex problems at the intersection of Soft Matter and Fluid Physics, developing new insights and technologies. Our studies have elucidated several intriguing advanced physical phenomena through a synergy of experiment, theory, and simulations. The studies have led to significant advancements to existing knowledge in terms of new experimental protocols, unique observations, new theoretical formulation, and critical physical insights hitherto unexplored. Our studies have involved flows inside confined geometries such as microchannels and microcavities, involving particles, drops, and bubbles, with varying viscous and elastic properties, relying on the inherent hydrodynamics or external fields such as ultrasound and magnetic fields. The advancements in physics in several research problems have spurred the development of microfluidics technology for several diagnostics and healthcare applications. In addition, we are also committed to advancing education and training in the field through online courses, workshops, and conferences and by serving on editorial boards and scientific committees.

We are funded by the Institutes of Eminence (IoE) scheme, Govt. of India.

Links: ICOM 2023     ICOM Talks     Hydrobio 2024

SELECTED RECENT PUBLICATIONS

  • Surfing droplets on nanoscopic films driven by surface acoustic waves, N. S. Satpathi, L. Malik, S. Nandy, T. Sujith, L. Y. Yeo, and A. K. Sen, Physical Review E, 2024. 

  • Reversible stream drop transition in a microfluidic coflow system via on demand exposure to acoustic standing waves, E.Hemachandran, S.Z.Hoque, T.Laurell, A.K.Sen, Physical Review Letters, 2021. 

  • Fluid viscoelasticity affects ultrasound force field induced particle transport, T. Sujith, L. Malik, and A. K. Sen, Journal of Fluid Mechanics, 2024.

  • Cassie-Wenzel wetting transition on nanostructured superhydrophobic surfaces induced by surface acoustic waves, A. Sudeepthi, L. Yeo and A. K. Sen, Applied Physics Letters, 2020.

  • Microfluidics-based rapid measurement of nitrite in human blood plasma, R. Gaikwad, P. R. Thangaraj, and A. K. Sen, Analyst, 2022.

  • Localized surface plasmon resonance (LSPR) biosensor based on thermally annealed silver nanostructures with on-chip blood-plasma separation for the detection of dengue non-structural protein NS1 antigen, Pearlson P. S., A. K. Sen, Biosensors and Bioelectronics, 2019.

  • Attraction and Repulsion between Liquid Droplets over a Liquid-impregnated Surface, B. Majhy, S. K. Jain and A. K. Sen, J. Phys. Chem. Lett. 11, 23, 10001–10006, 2020

  • Ultrasound resonance in coflowing immiscible liquids in a microchannel, S. Z. Hoque and A. K. Sen, Physical Review E, 2023.

  • Interfacial instability in a viscoelastic microfluidic coflow system, S. Hazra, L. Malik, T. Sujith, and A. K. Sen, Journal of Fluid Mechanics, 2024. 

  • Optomicrofluidic device for detection and isolation of drop encapsulated target cells in single-cell format, R. Gaikwad and A. K. Sen, Analyst, 2020.

     

  • Acoustic impedance based label-free isolation of circulating tumour cells from blood using acoustophoresis, S. Karthick, P. N. Pradeep, P. Kanchana and A. K. Sen, Lab on Chip, 2018.

  • Continuous electrical lysis of cancer cells in a microfluidic device with passivated interdigitated electrodes, K. Pandian, P. Ajanth, S. Z. Hoque, A. Sudeepthi, and A. K. Sen, Biomicrofluidics, 2020.

     

  • Ultrasound reforms droplets, L. Malik, S. Nandy, N. S. Satpathi, D. Ghosh, T. Laurell and A. K. Sen, Lab on Chip, 2024.

  •  Attraction and Repulsion between Liquid Droplets over a Liquid-impregnated Surface, B. Majhy, S. K. Jain and A. K. Sen, Journal of Physical Chemistry Letters, 2020.

     

ANNOUNCEMENTS

  • Prof. Ashis Kumar Sen has been inducted as a Fellow of the Royal Society of Chemistry (FRSC), UK.

  • Dr. Ashis Kumar Sen received the Institute Research & Development Awards (IRDA) – Mid Career Level Award, IIT Madras - 2021.

  • Dr. Karthick S, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at IITDM, Kancheepuram.

  • Dr. Hemachandran E, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at National Institute of Advanced Manufacturing Technology (NIAMT).

  • Dr. Sajeesh P, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at NSS College of Engineering.

  • Congratulations Dr. Ravindra Gaikwad for joining Saber Biotech, Paris, France as a Scientist.

  • Congratulations to Dr. Niladri S Satpathi and Dr. Lokesh Malik for joining as Post-Doctoral Fellow at University of Twente and Aalto University, respectively.

  • Rameez Iqbal and Mr. Utsab Banerjee, PhD scholars of our Lab, received the Institute Research Award (IRA) on recognition of their PhD research work, Congratulations!

  • Dr. Butunath Majhy, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at IIT Guwahati.

  • Sudeepthi A. and Utsab Banerjee won Best Student Presentation Awards at the 7th International and 45th National Fluid Mechanics and Fluid Power (FMFP) conference held at IIT Bombay during 10 - 12, December 2018.

  • Dr. Ashis Kumar Sen received The SwarnaJayanti Fellowship Award 2017 - 2018 (Engineering Sciences), Dept. of Science & Technology, India.

  • PhD scholar Ravindra Gaikwad (and Dr. Ashis Kumar Sen as mentor) received the SITARE-Gandhian Young Technological Awards 2020.

  • Dr. Jayaprakash K S, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at BITS Hyderabad.

  • Dr. Ashis Kumar Sen received the Young Faculty Recognition Award (YFRA) – 2017, IIT Madras.

     

  • Dr. Ashis Kumar Sen received the Institute Research & Development Awards (IRDA) – Early Career Level Award, IIT Madras - 2017.

     

  • Our work on capillary and acoustics based blood-plasma separation got selected for display in the Exhibition on Innovations in Medical Science and Bio Technology for Grassroots Applications on 09 March, 2017 at Rashtrapati Bhavan, New Delhi.
  • Our research work on “Capillary based blood-plasma separation” appeared in Hindu on 26 Sep 2016.
  • Dr. Ashis Kumar Sen received the Indian National Academy of Engineering (INAE) Young Engineer Award – 2013.
  • Dr. Ashis Kumar Sen received the Institute of Engineers India (IEI) Young Engineer Award – 2013.

  • Dr. Abhishek Raj, alumni (former PhD scholar) of our lab has joined as an Assistant Professor at IIT Patna.

FUNDING ACKNOWLEDGEMENT







Collaborators

  • Prof. Amy Shen, Okinawa Institute of Science and Technology, Japan.
  • Prof. Sushanta K Mitra, University of Waterloo, Canada.
  • Prof. Thomas Laurell, Lund University, Sweden.
  • Prof. Leslie Yeo, RMIT University, Australia.
  • Prof. Michael Baudoin, University of Lille, France.
  • Dr. Paul Ramesh, Cardiothoracic Surgeon, Apollo Hospitals, Chennai.
  • Dr. Kiran Raj, Department of AMBE, IIT Madras.
  • Prof. K M Muraleedharan, Department of Chemistry, IIT Madras.
  • Prof. Anil Prabhakar, Department of Electrical Engineering, IIT Madras.
  • Prof. Madhulika Dixit, Department of Biotechnology, IIT Madras.
  • Prof. Mukesh Doble, Department of Biotechnology, IIT Madras.
  • Prof. Sarit Kumar Das, Department of Mechanical Engineering, IIT Madras.